Schreiner MediPharm Enables Digital Adherence Monitoring with New Child-Resistant Smart Blister Wallet

Through partnership with Keystone Folding Box Co., the customizable blister package with individual cavity tracking provides a smart, secure packaging solution for clinical trials.

The Smart Blister Wallet based on Key-Pak® is child-resistant and enables real-time digital therapy monitoring in clinical trials.

Schreiner MediPharm, a Germany-based global provider of innovative functional label solutions for the healthcare industry, has partnered with Keystone Folding Box Co. to introduce a new smart blister pack with especially child-resistant, senior-friendly features. Ideal for clinical trials, the new solution utilizes integrated electronics to convert blister packaging into a real time e-diary for capturing dosing history data.

Schreiner MediPharm has developed a smart extension for the proven Key-Pak® wallet for oral solid dose medication, a signature offering from U.S.-based Keystone Folding Box Company. The novel, customizable blister wallet combines a child-resistant paperboard package with state-of-the-art technology for digital adherence monitoring, enhancing clinical trial reporting accuracy.

Keystone is a leader in paperboard pharmaceutical packaging whose Key-Pak® wallet card has become a mainstay in clinical trials. To Key-Pak®, Schreiner MediPharm has added electronic functions for medication adherence monitoring with numerous benefits.

The distinguishing characteristic of the “smart” Key-Pak® wallet is the integration of conductive trace-patterns linked to each of the wallet card’s cavities. As a result, data is generated at the instant the patient removes a dose from the wallet. The details, such as time and date of dose removal and specific cavity location, are stored within the electronics inside the package, and can be transmitted by means of NFC or Bluetooth technology for precise patient compliance tracking.

There is also an option to send medication dosing reminders to patients, and to adjust therapy plans as needed. When used in combination with special software, central tracking as well as data documentation and analysis can be achieved.

The Smart Blister Wallet based on Key-Pak® is both child-resistant and senior-friendly. Patient ease of use, in terms of accessing each dose, is accomplished by a push-through safety feature that is a hallmark of the Key-Pak® design. Pharmaceutical companies are provided with a flexible solution that can be customized to any clinical trial and its dosing scheme, such as the number of cavities, blister arrangement, and varying pill shapes.

By enhancing data quality and optimizing processes, the Smart Blister Package can shorten trial duration, thereby accelerating the approval process for new drugs. In addition, Schreiner MediPharm’s scalable, state-of-the-art manufacturing processes ensure end-to-end automated production. This innovative packaging solution increases efficiency and flexibility in clinical research settings, and emphasizes patient safety and comfort.

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